Virus Vector - Viral Vector Production

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The world’s first red fluorescent potassium sensors, RGEPO1/2, are here!

Precision Gene Delivery to Brain Blood Vessels: A New Tool for Studying Cerebrovascular Diseases—rAAV-miniBEND

New Products Discover Latest Neuroscience Viral Tools & Sensors

Breakthrough | WESTLAKE UNIVERSITY TEAM DEVELOPS HIGH-PERFORMANCE RED GENETICALLY ENCODED CALCIUM PROBE“SOMAFRCAMP!”WITH SENSITIVITY MATCHING TO GCAMP!

Client Publication | Neuron | Collaborative Discovery by Dr. Juan Song’s Team at UNC Reveals Distinct Circuit Targets for Cognitive and Emotional Deficits in Alzheimer’s Disease

Year-End Research Sale 2025 : A Unified Thanksgiving–Black Friday–Cyber Monday Promotion

Enhancer AAV Vectors, a breakthrough for genetic research!

Pioneering Innovation in Gene Vector Research

With a focus on advanced neuroscience, we provide advanced technology platforms
to lead the innovation of viral tools for medical research.

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Brain Case provides a variety of vector tools, including AAV, lentivirus, rabies virus, and herpes simplex virus, for gene regulation, gene editing, as well as in vitro and in vivo experiments.

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Brain Case is a leading biotech company specializing in viral vectors for neural circuits, gene therapy, and tumor immunotherapy, with advanced GMP platforms.

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🧠 Year-End Research Sale 2025 : A Unified Thanksgiving–Black Friday–Cyber Monday Promotion✨

Holiday research sale featuring AAVs, PRV/HSV/RV/VSV tools, combo packs, mystery boxes, and custom virus packaging discounts. Nov 24–Dec 7.

Nat Biomed Eng | Woo-ping Ge and Wenzhi Sun’s teams develop the rAAV-miniBEND system: Breaking thro

rAAV-miniBEND: Gene delivery to brain endothelial cells and modeling of vascular malformation diseases.

With the Help of Dual-Color Photoreceptive Proteins, Optical Activation and Inhibition Can Also Be Pe

A dual-color, bidirectional optogenetic tool, eNPAC2.0 and somBiPOLES, was developed.

Featured Content

Literature Highlight | “Red–Green Sensors” Enable Full-Field, Dynamic Visualization of L-Lactat

These probes enable spectrally and spatially multiplexed imaging of extracellular and intracellular L-lactate in cultured cells (e.g., HeLa cells, neurons), brain slices, and live mice.

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Client Publication | Adv. Sci. | Nanjing University Team Led by Prof. Jingning Zhu Uncovers a Novel M

Optogenetic study shows H4R excites RVMM GABAergic neurons via TRPV1, suppressing sympathetic activity and lowering blood pressure.

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Sci. Adv. | Patch-clamp study reveals a new mechanism of brain aging: how autophagy defects in OPCs “

New study reveals how impaired autophagy in OPCs accelerates brain aging and cognitive decline through CCL3/CCL5–CCR5 signaling. Brain Case offers full electrophysiology testing and analysis support.

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Science | Unveiling the New Reward Center: From a Mysterious Nucleus Cluster to the Emotional Code

It reveals the function of SVTg as a new brainstem reward center, which processes emotional value by integrating inputs from cortical and subcortical regions.

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Client Publication | Nature Communications | Xiangya Second Hospital team led by Dr. Ruping Dai and D

Scientists from Xiangya Second Hospital reveal how hypothalamic CRH neurons regulate the sympathetic–neutrophil axis to protect against acute lung injury.

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Breakthrough! Chinese Team Publishes in Cell: Gene-Edited Stem Cells Rejuvenate Aging Monkeys

Chinese researchers developed FOXO3 gene-edited stem cells that reversed aging in primates. The study, published in Cell, reveals exosome-mediated systemic rejuvenation.

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Client Publication | Nature Communications | Collaborative Study by Prof. Zhong Chen (Zhejiang Chines

On August 29, the research team led by Prof. Zhong Chen and Qingming Luo published “A whole-brain male mouse atlas of long-range inputs to histaminergic neurons.”

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Client Publication | Neuron | Collaborative Discovery by Dr. Juan Song’s Team Reveals Distinct Cir

Dr. Juan Song’s team published “Segregated supramammillary–dentate gyrus circuits modulate cognitive and affective function in healthy and Alzheimer’s disease model mice.”

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