Explore the critical quality attributes (CQA) of AAV vectors, including identity, potency, purity, impurities, and safety, for safe and effective gene therapy.
A breakthrough red–green dual-sensor system enables high-resolution, minimally invasive in vivo imaging of L-lactate dynamics in awake mice, revealing metabolic–neuronal coupling.
R-eLACCO2.1 is a red fluorescent genetically encoded sensor enabling in vivo, cell-resolution imaging of extracellular L-lactate and neural activity in awake mice, fully compatible with GCaMP and FLIM.
A PNAS study reveals how linoleic acid and (Z)-9-tricosene, detected via the main olfactory system, interact with the VTA–mOT dopaminergic pathway to regulate rodent insect predation.
