Explore the critical quality attributes (CQA) of AAV vectors, including identity, potency, purity, impurities, and safety, for safe and effective gene therapy.
A breakthrough red–green dual-sensor system enables high-resolution, minimally invasive in vivo imaging of L-lactate dynamics in awake mice, revealing metabolic–neuronal coupling.
R-eLACCO2.1 is a red fluorescent genetically encoded sensor enabling in vivo, cell-resolution imaging of extracellular L-lactate and neural activity in awake mice, fully compatible with GCaMP and FLIM.
Learn how to solve AAV expression loss and weak fluorescence with step-by-step optimization of vector design, viral titer, injection dose, timing, detection, and sample processing.