Pioneering Innovation in Gene Vector Research

E-mail：BD@ebraincase.com

Tel：+8618971215294

neuroscience viral vectors, optogenetics, chemogenetics, neurotransmitter sensors, GCaMP, neural circuit research, AAV vectors

Fluorescent “superheroes”！ mBaoJin + mScarlet3-H (also known as mYongHong) Tool Viruses Empower Super-Resolution and High-Efficiency Imaging

New Products Discover Latest Neuroscience Viral Tools & Sensors

Precision Gene Delivery to Brain Blood Vessels: A New Tool for Studying Cerebrovascular Diseases—rAAV-miniBEND

The world’s first red fluorescent potassium sensors, RGEPO1/2, are here!

A New Tool for Visualizing α-Syn Aggregates in Live Brains—α-Syn-6H-EGFP/tdT sensor Experiment Guide

Breakthrough | WESTLAKE UNIVERSITY TEAM DEVELOPS HIGH-PERFORMANCE RED GENETICALLY ENCODED CALCIUM PROBE“SOMAFRCAMP!”WITH SENSITIVITY MATCHING TO GCAMP!

Client Publication | Neuron | Collaborative Discovery by Dr. Juan Song’s Team at UNC Reveals Distinct Circuit Targets for Cognitive and Emotional Deficits in Alzheimer’s Disease

Pioneering Innovation in Gene Vector Research

With a focus on advanced neuroscience, we provide advanced technology platforms
to lead the innovation of viral tools for medical research.

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Pre-made AAV Library

Brain Case provides a variety of vector tools, including AAV, lentivirus, rabies virus, and herpes simplex virus, for gene regulation, gene editing, as well as in vitro and in vivo experiments.

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New Research Tools

The toolkits you’ve been looking for, presented by Brain Case

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Support

Brain Case shares the scientific achievements of product users and provides practical techniques and tips.

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News

A Novel Serotype for Peripheral Retrograde Tracing — AAV9-Retro

Discover AAV9-Retro, a novel AAV serotype combining efficient retrograde tracing with BBB crossing capability for neural circuit research and CNS gene delivery.

Meet the New Stars of Red Calcium Imaging! PinkyCaMP & SomaFRCaMPi Tool Viruses for Advanced Neur

Meet PinkyCaMP and SomaFRCaMPi, next-generation red GECI tool viruses designed for brighter, cleaner, and more sensitive in vivo calcium imaging.

PRV Tracers for Peripheral Neural Circuit Tracing | Representative Applications Across Multiple Organ

Explore BrainCase PRV Tracers for peripheral neural circuit tracing. Discover retrograde transsynaptic mapping across multiple organs with validated research applications.

Featured Content

Sci. Adv.丨Could Intranasal Oxytocin Help Police Officers Prevent PTSD? Xiao Lei’s Team from Fudan

A Science Advances study reveals how oxytocin suppresses fear learning through prelimbic cortex SST interneuron circuits, offering insights into PTSD prevention.

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How to Choose the Right Green Calcium Imaging Tool? From GCaMP6 to jGCaMP8 — This Guide Explains Ev

A complete guide comparing GCaMP6, jGCaMP7, jGCaMP8 and RiboL1-jGCaMP8, covering sensitivity, kinetics, soma targeting and RO-injection brightness performance.

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Client Article | Advanced Science | Team led by Changgeng Peng, Rougang Xie, Xin Yu, Xiafeng Shen, et

Discovery of Nav1.7/Nav1.8/TrkB SMAC reveals a cytoskeletal ion channel complex driving neuropathic pain and supports dual-target blockade therapy.

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Client Articles | Neuron | Can’t sleep well under stress? Air Force Medical University team (Hailon

A Neuron study reveals how chronic stress activates VTA–mPFC dopamine burst firing, leading to excessive cortical dopamine, disrupted sleep spindles, and fragmented NREM sleep.

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Distinguishing ssAAV and scAAV in One Article: Avoid Pitfalls in AAV Vector Selection

Comprehensive guide to ssAAV vs scAAV, including Definitions、 Applications(Gene Editing, miRNA Overexpression, Target Gene Overexpression) and Selection Recommendations.

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Bone Section | Applications of AAV in Gene Therapy: Serotype Selection, Promoter Choice, and Injectio

A review of AAV-based gene therapy in bone diseases, including serotype selection, injection strategies, and preclinical studies in osteoarthritis and osteoporosis.

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Customer Article | Sci. Adv. | Jinhao Sun’s Team at Shandong University Unveils: How Does the Brain

Shandong University study reveals Hcn1-dependent PVN engram neurons encode gastric inflammatory memory, linking stress, HPA axis, and chronic gastritis.

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Sci. Adv. | How Does the Brain Recognize Familiar Individuals? Hao Wang / Gao Chen / Hongbin Yang / L

Science Advances reveals that MeApv VGluT2 neurons encode conspecific identity and store social memory, providing new insights into social recognition circuits.

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A New Tool for Visualizing α-Syn Aggregates in Live Brains—α-Syn-6H-EGFP/tdT sensor Experiment Gu

The α-Syn-6H-EGFP/tdT sensor provides a comprehensive solution for α-synucleinopathy research, covering aggregate labeling, in vivo tracking, and drug screening.

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Tool viruses: humanity’s domesticated biological couriers

Tool viruses (viral vectors) are engineered biological delivery systems widely used in gene therapy, cell therapy, neuroscience, and vaccine development. This article covers Viral structure and applications in modern biomedical research.

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Tel： +8618971215294

E-mail： BD@ebraincase.com