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Bidirectional control of parathyroid hormone and bone mass by subfornical organ

Bidirectional control of parathyroid hormone and bone mass by subfornical organ

Parathyroid hormone (PTH) is one of the key hormones regulating bone metabolism and calcium balance. However, how the central nervous system regulates PTH remains unclear. The subfornical organ (SFO), located above the third ventricle, is known to regulat

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Social impairments induced by chronic social isolation stress

Social impairments induced by chronic social isolation stress

Social isolation stress is a widespread and pervasive issue in modern society. Even before the unprecedented COVID-19 pandemic, social isolation was prevalent globally, affecting nearly 40% of the population in some countries. During the COVID-19 pandemic

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Muscle Insights丨Applications of AAV in Gene Therapy: Serotype, Promoter Selection, and Injection Strategies

Muscle Insights丨Applications of AAV in Gene Therapy: Serotype, Promoter Selection, and Injection Strategies

Muscle Insights丨Applications of AAV in Gene Therapy: Serotype, Promoter Selection, and Injection Strategies | Brain Case

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Breakthrough | Li Xiaojiang/Lai Liangxue team uses AAV gene therapy to treat Huntington's disease pigs

Breakthrough | Li Xiaojiang/Lai Liangxue team uses AAV gene therapy to treat Huntington's disease pigs

Huntingtons disease Huntingtons disease (HD) is a rare autosomal dominant genetic disease. Patients typically present in middle age and experience motor, cognitive, and psychiatric symptoms. The clinical symptoms of Huntingtons disease are complex and cha

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