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Nature Breakthrough: AAV-ROOT Serotype Enables Precise Tracing of Fat-Sensing Neurons, Challenging Traditional Metabolic Regulation Concepts

Nature Breakthrough: AAV-ROOT Serotype Enables Precise Tracing of Fat-Sensing Neurons, Challenging Traditional Metabolic Regulation Concepts

This study revealed the role of DRG sensory innervation in regulating adipose tissue function, particularly through a novel AAV serotype—ROOT.

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Exploring the "Jumpers" of the Genome (Part 1): The Application of Tol2 Transposon in Gene Function Research

Exploring the "Jumpers" of the Genome (Part 1): The Application of Tol2 Transposon in Gene Function Research

The Tol2 transposon system, known for its efficiency and flexibility, has become an important tool in gene editing and gene therapy.

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Cell︱Precise Pain Control: HCAD System Revolutionizes Peripheral Chemogenetics

Cell︱Precise Pain Control: HCAD System Revolutionizes Peripheral Chemogenetics

Precise Pain Control | Professor Bryan L. Roth’s team developed the HCAD system, a DREADD-based chemogenetic tool utilizing the hydroxycarboxylic acid receptor 2 (HCA2).

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Autism Spectrum Disorder (ASD): Historical Origins, Etiology Exploration, and New Dawn in Treatment

Autism Spectrum Disorder (ASD): Historical Origins, Etiology Exploration, and New Dawn in Treatment

ASD research has evolved from outdated theories to groundbreaking developments in neurobiology, precision medicine, and AI, highlighting the need for personalized, multi-level interventions.

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