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Pancreas Series | Application of AAV in Gene Therapy: Serotype, Promoter Selection, and Injection Strategies

Pancreas Series | Application of AAV in Gene Therapy: Serotype, Promoter Selection, and Injection Strategies

Application of AAV in Gene Therapy | Studies shown AAV vectors demonstrate higher transduction efficiency in the pancreas compared to adenoviral and lentiviral vectors

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GLPLight1 sensor: A Revolutionary Tool for Diabetes Treatment, Opening a New Era of Precise Monitoring and Drug Screening!

GLPLight1 sensor: A Revolutionary Tool for Diabetes Treatment, Opening a New Era of Precise Monitoring and Drug Screening!

This study developed a genetically encoded sensor, GLPLight1, with high sensitivity and temporal resolution, capable of real-time, high spatiotemporal resolution monitoring of GLP-1 signals and the activation dynamics of human GLP-1R.

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Bidirectional control of parathyroid hormone and bone mass by subfornical organ

Bidirectional control of parathyroid hormone and bone mass by subfornical organ

Parathyroid hormone (PTH) is one of the key hormones regulating bone metabolism and calcium balance. However, how the central nervous system regulates PTH remains unclear. The subfornical organ (SFO), located above the third ventricle, is known to regulat

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Social impairments induced by chronic social isolation stress

Social impairments induced by chronic social isolation stress

Social isolation stress is a widespread and pervasive issue in modern society. Even before the unprecedented COVID-19 pandemic, social isolation was prevalent globally, affecting nearly 40% of the population in some countries. During the COVID-19 pandemic

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