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Literature Insight | Combining Optogenetics, Calcium Imaging, and Retrograde Viral Tracing in Organoids: Decoding Cortico-Striatal Circuit Connectivity

Literature Insight | Combining Optogenetics, Calcium Imaging, and Retrograde Viral Tracing in Organoids: Decoding Cortico-Striatal Circuit Connectivity

Human cortico-striatal organoids enable retrograde viral tracing, optogenetics, and calcium imaging to model circuit development and disease.

Client Article | Zixuan He & Xiaojuan Zhu’s Team at Northeast Normal University | A medial habenula neural circuit controlling anxiety-like behaviors in response to acute stress

Client Article | Zixuan He & Xiaojuan Zhu’s Team at Northeast Normal University | A medial habenula neural circuit controlling anxiety-like behaviors in response to acute stress

The IFVGLUT→MHbTac1→IPLVGLUT circuit regulates anxiety-like behaviors in mice. Study reveals MHb neurons, acute stress, and neural circuitry roles.

Client Article | Sci. Transl. Med. | Xiaodong Liu & Changyu Jiang’s Team Reveals a New Mechanism of Microglial Remodeling of Spinal Pain Microcircuits—Synaptic Pruning

Client Article | Sci. Transl. Med. | Xiaodong Liu & Changyu Jiang’s Team Reveals a New Mechanism of Microglial Remodeling of Spinal Pain Microcircuits—Synaptic Pruning

Reveals a New Mechanism of Microglial Remodeling of Spinal Pain Microcircuits—Synaptic Pruning

Literature Review | Major Nature Discovery: GABAergic Neurons Drive Diffuse Midline Glioma Growth via Synaptic Signaling

Literature Review | Major Nature Discovery: GABAergic Neurons Drive Diffuse Midline Glioma Growth via Synaptic Signaling

Nature study reveals GABAergic synapses between neurons and H3K27M+ DMG cells promote tumor growth, offering new insights for brain cancer therapy.

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