Features: Based on wild-type mouse α-Syn, α-Syn was fused with fluorescent proteins (EGFP/tdTomato) through a 6-histidine (6H) linker. After optimization of seven linker variants, the 6H linker achieved the core characteristics of efficient incorporation of the probe into α-Syn aggregates and the absence of spontaneous self-aggregation.
Applications:
α-Syn aggregate imaging
Aggregate propagation studies
Drug screening
In vivo functional studies
Gene/Insert name：mSnca-6H
Tag/Fusion protein：tdTomato (Red, Ex λ 554, Em λ 581)
Titer: ＞5.0e+13 VG/mL
Volume：100 μL
