BrainCase Biotech| Whole-Brain Transparency Imaging and Analysis Services ()
💠 Virus Injection Sample Imaging and Neural Circuit Analysis
💠 Differential Neuron Activation in the Brain (cFos Immunofluorescence Labeling and Analysis)
Service Overview
By employing efficient sample transparency and imaging technologies, we analyze the entire neural network of mice. This service achieves full-body tissue transparency while maintaining fluorescence protein signals. Whole-mouse, uniform subcellular resolution imaging is completed within 40 hours, enabling high-precision 3D reconstruction of neural networks. We support various techniques, including immunolabeling, viral tracing, and transgenic marking, to comprehensively display the interactions between neurons and other tissues.
Imaging Performance
💠Resolution: Up to 0.5 x 0.5 x 2.5 μm³
💠Imaging Throughput: Under high resolution, up to 1.0 trillion pixels of data can be acquired per hour
💠Imaging Speed: Whole-brain imaging of a mouse completed in less than 2 hours
💠Laser Sources: Equipped with 405 nm, 488 nm, 552 nm, and 640 nm wavelengths for excitation
Case Showcase
Differential Neuron Activation (c-Fos) Counting Analysis in Mouse Brain
Labeling Tool: c-Fos Antibody Staining
Whole-Brain Neuron Imaging of Thy-GFP Mice
Spinal Cord Segmental Neural Tracing in Mice Labeling Tool: RV-△G-EGFP
Retrograde Labeling of Excitatory Neurons from the Pedunculopontine Nucleus (PPN)
Labeling Tool: AAV Virus
For inquiries or to discuss how our whole-brain imaging and
neural circuit analysis services can support your research,
please contact us at bd@ebraincase.com
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