Features:The optimized mPro723 promoter exhibited high expression activity in endothelial cells, and certain cis-regulatory elements effectively suppressed off-target transcription in non-endothelial cells, among which mCis700 showed the most pronounced effect.
Cre is a recombinase derived from bacteriophage P1. This enzyme functions through a topoisomerase I-like mechanism at two DNA recognition sites (LoxP sites).