Features: mYongHong (also known as mScarlet3-H) is a groundbreaking monomeric red fluorescent protein engineered for demanding microscopy applications. It offers exceptional stability across preparation methods and imaging techniques:
Correlative Light and Electron Microscopy (CLEM): With 500% greater resistance to osmium tetroxide and a 20-fold enhancement in signal-to-noise ratio (SNR) compared to first-generation probes like mEosEM, mYongHong enables high-SNR imaging of organelles such as mitochondria, ER, lipid droplets, the nuclear envelope, and nuclei.
Rapid Tissue Clearing: Retains 90% of its fluorescence after 1 hour at 90 °C, allowing a whole-brain clearing process in mice to be completed in just 24 hours while maintaining strong fluorescence for 3D imaging.
Superior Photostability: Ideal for long-term live-cell applications, especially 3D-SIM and STED super-resolution imaging, where sustained fluorescence is critical.
Gene/Insert name: mYongHong Tag/Fusion protein: mYongHong Titer：>1x10^13 VG/mL，>2x10^12 VG/mL Volume：100μL
Brain Case is honored to have received authorization from Zhifei Fu’ s laboratory to produce various tool vectors for mYongHong. For inquiries, please contact Zhifei Fu’ s laboratory (fuzhifei@fjmu.edu.cn), or reach out to Brain Case at BD@ebraincase.com.
