Features：Researchers explored topological inversion and soma-localized strategies, designing a red gene-encoded calcium ion indicator—FRCaMPi(for enhanced in vivo performance). It demonstrated up to 2-fold higher dynamic range and single action potential (AP) peak ΔF/F0 compared to the widely used jRGECO1a in cultured neurons and in vivo experiments.

Gene/Insert name：FRCaMPi

Tag/Fusion protein：mApple

Titer：>1x10^13 VG/mL，>2x10^12 VG/mL

Volume：100μL

Brain Case is honored to have received authorization from Professor Kiryl’s laboratory to produce various tool vectors for FRCaMPi and SomaFRCaMPi. For inquiries, please contact Kiryl’s laboratory (kiryl.piatkevich@westlake.edu.cn and zhoushihao@westlake.edu.cn), or reach out to Brain Case at BD@ebraincase.com.