Manifested as persistent low spirits and mood disorders, is one of the most common and prominent mental disorders worldwide.
Alzheimer's disease(AD) is a common neurodegenerative disease. There are many experimental animal models of AD that are commonly used, which exhibit different disease symptoms and pathological changes.
Compared to the commonly used jRGECO1a, SomaFRCaMPi exhibits a broader dynamic range, higher peak ΔF/F₀, and an improved signal-to-noise ratio (SNR).
We aim to develop AAV serotypes that are more efficient and precise in targeting specific tissues or cell types, thus serving fields such as gene therapy and cell therapy.